Although the human data aren’t (yet) published, the researchers have also performed similar studies of high-fat diets in healthy young men who then performed exercise and (cognitive) tests. Dr. Murray said he is still (reviewing) the data, but the short-term effect of a fatty diet on humans appears to be similar to that found in the rat studies. It’s not clear why fatty foods would cause a short-term decline in cognitive function. One theory is that a high-fat diet can (trigger) insulin (resistance), which means the body becomes less (efficient) at using the glucose, or blood sugar, so important to brain function. Fatty foods appear to have a short-term effect on exercise performance because the body reacts to high fat content in the blood by releasing certain (proteins) that essentially make the metabolism less efficient. “It’s thought to be a protective mechanism to get rid of excess fat,’’ Dr. Murray said. “But it was making (muscles) less efficient at using oxygen and (fuel) to make the energy needed to run.’’ The findings are (particularly) relevant to people who may not worry about (binging) on fatty foods because they exercise regularly. "Exercise is a good way of burning it off, because you’re burning the calories off,’’ Dr. Murray said. “But in terms of actually trying to put in a good time if you’re (running), it will limit your performance."
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